Few inputs can reprogram biological networks
نویسندگان
چکیده
منابع مشابه
Breaching Euclidean distance-preserving data perturbation using few known inputs
We examine Euclidean distance preserving data perturbation as a tool for privacy-preserving data mining. Such perturbations allow many important data mining algorithms, with only minor modification, to be applied to the perturbed data and produce exactly the same results as if applied to the original data, e.g. hierarchical clustering and k-means clustering. However, the issue of how well the o...
متن کاملNeural Networks with Few Multiplications
For most deep learning algorithms training is notoriously time consuming. Since most of the computation in training neural networks is typically spent on floating point multiplications, we investigate an approach to training that eliminates the need for most of these. Our method consists of two parts: First we stochastically binarize weights to convert multiplications involved in computing hidd...
متن کاملThe role of ongoing spatio-temporal activity on shaping responses to inputs in biological networks
Biological systems such as networks of neurons are able to produce a wide range of intrinsic patterns such as waves and synchronous oscillations. On the other hand, these systems must constantly respond to external stimuli. The goal of this project is to find conditions generating complex spatio-temporal activity in these networks networks and then use various mathematical tools to examine how ...
متن کاملNever Reprogram Again
DSLGen (Domain Specific Language Generator) is a program generation system in which application programs can be written in a domain specific language that is independent of the execution platform architecture and yet can be targeted to arbitrary existing and future execution platforms in a way that exploits the performance or computation improvement opportunities specific to those platforms. Th...
متن کاملCD137 Agonist Therapy Can Reprogram Regulatory T Cells into Cytotoxic CD4+ T Cells with Antitumor Activity.
Recent successes in immune therapeutic strategies aimed to improve control over tumor growth have sparked hope that long-lived control of cancer through stimulation of the immune system can be possible. However, the underlying immunological mechanisms that are induced by immunotherapeutic strategies are not well understood. In this study, we used the highly immunogenic Friend virus-induced FBL-...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 2011
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature10543